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Invitrogen
SV40 T-Antigen Monoclonal Antibody (PAb419)
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产品信息
MA1-90660
应用
建议稀释比
已发表文章
产品规格
种属反应
Virus
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
PAb419
抗原
Full length protein (SV40).
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.05M sodium phosphate with 0.2% gelatin
内含物
0.1% sodium azide
保存条件
4°C, do not freeze
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody recognizes the 94 kDa SV40 large T antigen and the 20.5 kDa SV40 small T antigen. Recommended positive controls include SV80 or SV-T2 cells.
靶标信息
The SV40 T antigen is encoded by the early region of the SV40 genome. The large T antigen binds DNA, and complexes with a 53,000 dalton cellular protein, p53, which is required for initiation of viral DNA replication during lytic growth. In addition, the large T antigen binds DNA polymerase and the transcription factor AP-2 and forms a specific complex with the P105 product of the retinoblastoma susceptibility gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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