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Abnova
SYNE3 Recombinant Rabbit Monoclonal Antibody
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产品信息
RAB04927
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
偶联物
形式
Liquid
纯化类型
Affinity chromatography
保存液
50mM tris glycine, pH 7.4, with 40% glycerol, 0.05% BSA, 150mM NaCl
内含物
0.01% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: KASH domain-containing protein 3; KASH3; Nesprin-3; Nuclear envelope spectrin repeat protein 3; spectrin repeat containing, nuclear envelope family member 3
基因别名: C14orf139; C14orf49; LINC00341; Nesp3; NET53; SYNE3
UniProt ID: (Human) Q6ZMZ3
Entrez Gene ID: (Human) 161176
