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Invitrogen
Saccharin Recombinant Mouse Monoclonal Antibody (2C5)
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Saccharin Antibody (MA566329) in SDS-PAGE
SDS-PAGE characterization of Saccharin under reducing conditions. Lane M: Protein marker (kDa); Lane SAC: Purified Saccharin Recombinant Monoclonal (Product # MA566329). Saccharin showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-651.
产品信息
MA566329
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
2C5
抗原
Conjugate of SAC hapten and KLH.
偶联物
形式
Liquid
浓度
7.7 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Saccharin, a widely used artificial sweetener, has been studied for its impact on bacterial cell envelope stability and its potential to influence the gut microbiome, which can ultimately affect human health. Despite its long history in the human diet, the mechanisms by which saccharin affects bacteria are not fully understood. Saccharin is also considered an emerging contaminant in water sources, and research has explored its degradation using metal organic frameworks. Additionally, saccharin serves as a scaffold in drug discovery, with various derivatives synthesized for pharmacological screening, including potential local anesthetics. These derivatives include 2-ethyl, 2-propyl, and other alkylated saccharins. Saccharin's effects on gut microbiota and glucose intolerance have been investigated, with studies indicating that short-term consumption at high doses does not significantly alter gut microbiota or induce glucose intolerance in healthy individuals.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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