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Invitrogen
Sarafloxacin Recombinant Mouse Monoclonal Antibody (2G5)
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Sarafloxacin Antibody (MA566326) in SDS-PAGE
SDS-PAGE characterization of Sarafloxacin under reducing conditions. Lane M: Protein marker (kDa); Lane SAR: Purified Sarafloxacin Recombinant Monoclonal (Product # MA566326). Sarafloxacin showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-425.
产品信息
MA566326
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
2G5
抗原
Conjugate of SAR hapten and KLH.
偶联物
形式
Liquid
浓度
7.8 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Sarafloxacin is a fluoroquinolone antibiotic developed for veterinary use, particularly effective in treating bacterial infections in poultry, fish, and other livestock. Structurally, sarafloxacin features a quinolone core, enriched with a fluorine atom, which enhances its antimicrobial activity by inhibiting bacterial DNA gyrase and topoisomerase IV, crucial enzymes in DNA replication and transcription processes. This mechanism of action makes sarafloxacin highly effective against a wide range of Gram-negative and some Gram-positive bacteria. Although initially utilized to improve animal health and reduce morbidity in farmed species, sarafloxacin's use has been restricted or phased out due to concerns about antibiotic resistance and potential environmental impacts. Its residues in food products and ecosystems, alongside the emergence of resistant bacterial strains, have prompted regulatory scrutiny and the exploration of alternative treatments. Research efforts remain focused on understanding its pharmacokinetic properties and interactions to inform safer veterinary practices.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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