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Alomone Labs, LTD
Secretin Receptor (extracellular) Polyclonal Antibody
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图: 1 / 4
Secretin Receptor (extracellular) Antibody (AGR-026-200UL) in IHC (F)
Expression of Secretin Receptor in mouse cerebellum - Immunohistochemical staining of perfusion-fixed frozen mouse brain sections with Anti-Secretin Receptor (extracellular) Antibody (#AGR-026), (1:200), followed by goat Anti-rabbit-AlexaFluor-488. A. Secretin Receptor immunoreactivity (green) appears in Bergmann glia profiles (vertical arrows point at Bergmann cell bodies and horizontal arrows at Bergmann ... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
AGR-026-200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide (C)NSFNERRHAYLLKLK, corresponding to amino acid residues 129-143 of rat Secretin Receptor, Extracellular, N-terminus
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
0.8 mg/mL
规格
160 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
The protein encoded by this gene is a G protein-coupled receptor and belongs to the glucagon-VIP-secretin receptor family. It binds secretin which is the most potent regulator of pancreatic bicarbonate, electrolyte and volume secretion. Secretin and its receptor are suggested to be involved in pancreatic cancer and autism.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: G protein-coupled receptor; SCTR; G-protein coupled receptor; MYOP; pancreatic secretin receptor; SCT-R; unnamed protein product
基因别名: 6530402O03Rik; SECR; SR
UniProt ID: (Human) P47872, (Mouse) Q5FWI2, (Rat) P23811
Entrez Gene ID: (Human) 6344, (Mouse) 319229, (Rat) 81779
diet induced thermogenesis
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
cellular water homeostasis
response to nutrient levels
regulation of appetite
regulation of synaptic plasticity
positive regulation of lipid catabolic process
renal water absorption
regulation of cAMP/PKA signal transduction
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