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Invitrogen
Sintilimab Recombinant Human Monoclonal Antibody
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产品信息
MA5-42220
产品规格
种属反应
Human
宿主/亚型
Human
/ IgG4, kappa
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
抗原
Human PDCD1/PD1/CD279
偶联物
形式
Liquid
浓度
1.57 mg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Endotoxin level < 0.01EU/µg by LAL method
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.
靶标信息
Sintilimab is a fully human anti-PD-1 antibody for tumor immunotherapy. It adopts IgG4 molecular framework and modified its hinge region sequence (S228P). Sintilimab, as a programmed death receptor 1 (PD-1) blocker, can bind to PD-1 molecules on the surface of T cells and relieve the inhibitory effect of PD-1 pathway on T cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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