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Fabgennix
Slingshot homolog 1 Polyclonal Antibody, Biotin
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Product Details
SISHT-BIOTIN
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to unique amino acid sequence on Slingshot homolog 1 protein.
Conjugate
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hSSH-1L; Protein phosphatase Slingshot homolog 1; slingshot 1; slingshot 1L; slingshot homolog 1; slingshot-like 1; SSH-1L; SSH-like protein 1
Gene Aliases: AW551225; Gm1394; Gm1395; KIAA1298; mSSH-1L; SSH-1; SSH1; SSH1L
UniProt ID: (Human) Q8WYL5, (Mouse) Q76I79
Entrez Gene ID: (Human) 54434, (Mouse) 231637, (Rat) 304580
cell morphogenesis
protein dephosphorylation
regulation of actin polymerization or depolymerization
regulation of lamellipodium assembly
actin cytoskeleton organization
regulation of cellular protein metabolic process
peptidyl-tyrosine dephosphorylation
regulation of axonogenesis
cellular response to ATP
dephosphorylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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