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Sodium-Iodide Symporter Monoclonal Antibody (14F)
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产品信息
200-301-G49
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
14F
抗原
Sodium-Iodide Symporter Antibody was produced in mice by repeated immunizations raised against mannose binding protein hNIS fusion.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein G
保存液
PBS, pH 7.2, with 50% glycerol
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Human Sodium Iodide Symporter (hNIS) is responsible for iodide concentrating ability within thyroid follicular cells. It is a membrane bound glycoprotein with 13 membrane spanning domains and 14 extramembranous domains. It may represent an autoantigen in thyroid.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Na(+)/I(-) cotransporter; Na(+)/I(-) symporter; Na+/I- symporter; natrium iodide transporter; sodium-iodide symporter; sodium/iodide symporter; solute carrier family 5 (sodium iodide symporter), member 5; solute carrier family 5 (sodium/iodide cotransporter), member 5; solute carrier family 5 member 5; symporter; NIS
基因别名: NIS; TDH1
UniProt ID: (Human) Q92911, (Rat) Q63008
Entrez Gene ID: (Human) 6528, (Mouse) 114479, (Rat) 114613
organic acid:sodium symporter activity
protein binding
sodium:iodide symporter activity
iodide transmembrane transporter activity
solute:sodium symporter activity
monovalent anion:sodium symporter activity
transmembrane transporter activity
protein homodimerization activity
ion transmembrane transporter activity
symporter activity
thyroid hormone generation
sodium ion transport
iodide transport
sodium ion transmembrane transport
transmembrane transport
iodide transmembrane transport
cellular response to forskolin
cellular response to Thyroid stimulating hormone
cellular response to cAMP
cellular response to gonadotropin stimulus
transport across blood-brain barrier
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