Invitrogen

Sodium Potassium ATPase Recombinant Rabbit Monoclonal Antibody (3L6F0)

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说明书
实验方案
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Sodium Potassium ATPase Recombinant Rabbit Monoclonal Antibody (3L6F0)

产品信息

MA5-42645

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1:50,000-1:200,000
-

免疫组化（石蜡） (IHC (P))

1:400-1:4,000
-

免疫细胞化学 (ICC/IF)

1:100-1:1,000
-

酶联免疫吸附实验 (ELISA)

1 µg/mL
-
产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

3L6F0

抗原

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Na+/K+-ATPase (P05023).
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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2911786

产品详细信息

Positive test controls include: HeLa, 293T, Mouse Liver. The target is usually found in the following locations: Cell membrane, Melanosome, Multi-pass membrane protein.

Immunogen sequence: MGKGVGRDKY EPAAVSEQGD KKGKKGKKDR DMDELKKEVS MDDHKLSLDE LHRKYGTDLS RGLTSARAAE ILARDGPNAL TPPPTTPEWI KFCRQLFGGF

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: ATPase, Na+/K+ transporting, alpha 1 polypeptide; ATPase, Na+/K+ transporting, alpha 4 polypeptide; ATPase, Na+/K+ transporting, alpha polypeptide-like 2; ATPase, Na+K+ transporting, alpha 1; Na(+)/K(+) ATPase alpha-1 subunit; Na(+)/K(+) ATPase alpha-4 subunit; Na+/K+ ATPase 1; Na+/K+ ATPase 4; Na+/K+ ATPase alpha 4 subunit; Na+/K+ ATPase, alpha-D polypeptide; Na, K-ATPase, alpha-A catalytic polypeptide; Na,K-ATPase alpha-1 subunit; Na,K-ATPase catalytic subunit alpha-A protein; Na,K-ATPase subunit alpha-C; sodium pump 4; Sodium pump subunit alpha-1; Sodium pump subunit alpha-4; sodium-potassium ATPase catalytic subunit alpha-1; sodium-potassium ATPase catalytic subunit alpha-4; sodium-potassium-ATPase, alpha 1 polypeptide; sodium/potassium-transporting ATPase alpha-4 chain; Sodium/potassium-transporting ATPase subunit alpha-1; Sodium/potassium-transporting ATPase subunit alpha-4

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基因别名: ATP1A1; ATP1A4; ATP1AL2; Atpa-1; BC010319; Nkaa1b

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UniProt ID: (Human) P05023, (Human) Q13733, (Rat) P06685, (Mouse) Q8VDN2, (Mouse) Q9WV27, (Rat) Q64541

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Entrez Gene ID: (Human) 476, (Human) 480, (Rat) 24211, (Mouse) 11928, (Mouse) 27222, (Rat) 29132

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功能
sodium:potassium-exchanging ATPase activity protein binding ATP binding phosphatase activity protein kinase binding protein domain specific binding ankyrin binding potassium ion binding sodium ion binding ADP binding phosphatidylinositol 3-kinase binding chaperone binding steroid hormone binding metal ion binding nucleotide binding hydrolase activity primary active transporter
参与通路
regulation of the force of heart contraction regulation of sodium ion transport cellular sodium ion homeostasis regulation of blood pressure potassium ion import establishment or maintenance of transmembrane electrochemical gradient ATP hydrolysis coupled proton transport dephosphorylation cellular potassium ion homeostasis negative regulation of glucocorticoid biosynthetic process ion transmembrane transport sodium ion export from cell response to drug negative regulation of heart contraction positive regulation of heart contraction positive regulation of striated muscle contraction relaxation of cardiac muscle cardiac muscle contraction membrane hyperpolarization cellular response to mechanical stimulus cellular response to steroid hormone stimulus regulation of cardiac muscle cell contraction membrane repolarization membrane repolarization during cardiac muscle cell action potential cell communication by electrical coupling involved in cardiac conduction response to glycoside regulation of cardiac conduction potassium ion import across plasma membrane potassium ion transport sodium ion transport spermatogenesis fertilization sperm motility regulation of cellular pH regulation of membrane potential energy coupled proton transmembrane transport, against electrochemical gradient sodium ion transmembrane transport potassium ion transmembrane transport transport ion transport metabolic process
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