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Somatostatin Antibody (710968) in ICC/IF
Immunofluorescence was performed on fixed and permeabilized SH-SY5Y cells for detection of SST using SST Recombinant Rabbit Superclonal™ Antibody (Product # 710968, 2 µg/mL) and labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034, 1:2000). Panel a) shows representative cells that were stained for detection and localization of SST prot... View More
产品信息
710968
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
Expi293
分类
Recombinant Superclonal
类型
Antibody
克隆号
9HCLC
抗原
Peptide corresponding to Human SST (aa 89-115)
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.2
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
This antibody is predicted to react with Monkey, Goat, Sheep and Pig.
Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit Superclonal™ antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production. Note: Formerly called “Recombinant polyclonal antibody”, this product is now rebranded as “Recombinant Superclonal™ antibody”. The physical product and the performance remain unchanged.
靶标信息
The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Growth hormone release-inhibiting factor; prepro-somatostatin; preprosomatostatin; Somatostatin; somatostatin 28; somatostatin-14; somatostatin-28
基因别名: SMST; SOM; SRIF; SS; SST
UniProt ID: (Human) P61278, (Mouse) P60041
Entrez Gene ID: (Human) 6750, (Mouse) 20604
hyperosmotic response
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
cell-cell signaling
chemical synaptic transmission
response to nutrient
digestion
negative regulation of cell proliferation
hormone-mediated apoptotic signaling pathway
response to heat
response to acidic pH
regulation of cell migration
response to drug
response to amino acid
response to steroid hormone
