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Invitrogen
Sorbitol Dehydrogenase Monoclonal Antibody (12B10G2)
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Sorbitol Dehydrogenase Antibody (MA5-49298) in IHC (P)
Immunohistochemistry analysis of Sorbitol Dehydrogenase in paraffin-embedded section of human SM fatty carcinoma of the left kidney tissue. Heat mediated antigen retrieval was performed in EDTA buffer (pH 8.0, epitope retrieval solution). The tissue section was blocked with 10% goat serum. Samples were incubated with Sorbitol Dehydrogenase Monoclonal antibody (Product # MA5-49298) using a dilution of 2 μg/m... View More
产品信息
MA5-49298
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
12B10G2
抗原
E.coli-derived human Sorbitol Dehydrogenase/SORD recombinant protein (Position: N8-P357).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
no preservative
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Adding 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
Positive Control - WB: human Hela whole cell, human HepG2 whole cell, rat liver tissue tissue, rat kidney tissue, mouse liver tissue, mouse kidney tissue. IHC: human liver cancer tissue, human renal clear cell carcinoma tissue, human SM fatty carcinoma of the left kidney tissue, rat kidney tissue. Flow: U20S cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
靶标信息
Sorbitol dehydrogenase catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NADcofactor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: (R,R)-butanediol dehydrogenase; epididymis secretory sperm binding protein Li 95n; L-iditol 2-dehydrogenase; Polyol dehydrogenase; RDH; Ribitol dehydrogenase; SDH; Sorbitol dehydrogenase; sorbitol dehydrogenase 1; SORD 1; XDH; Xylitol dehydrogenase
基因别名: HEL-S-95n; Sdh-1; Sdh1; Sodh-1; SORD; SORD1
UniProt ID: (Human) Q00796, (Rat) P27867, (Mouse) Q64442
Entrez Gene ID: (Human) 6652, (Rat) 24788, (Mouse) 20322
glucose metabolic process
sorbitol catabolic process
response to osmotic stress
response to hormone
glucuronate catabolic process to xylulose 5-phosphate
sperm motility
response to nutrient levels
response to drug
fructose biosynthetic process
response to cadmium ion
response to copper ion
L-xylitol catabolic process
L-xylitol metabolic process
oxidation-reduction process
sorbitol metabolic process
