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Spectinomycin is an aminocyclitol antibiotic, distinct from aminoglycosides, primarily used for treating gonorrhea and organisms with multiple antibiotic resistance. It functions by inhibiting bacterial protein synthesis, making it effective against Neisseria gonorrhoeae, which has shown increasing resistance to other antibiotics like penicillin and ciprofloxacin. Structurally, spectinomycin is characterized by its aminocyclitol ring, and recent synthetic modifications have led to the development of more potent derivatives, such as N-ethylene linked aminomethyl spectinomycin (eAmSPCs), which exhibit enhanced activity against Mycobacterium abscessus. Despite its efficacy in certain infections, spectinomycin's poor antimycobacterial activity limits its use in tuberculosis treatment, prompting the creation of semisynthetic analogs with improved selectivity and potency.
仅用于科研。不用于诊断过程。未经明确授权不得转售。