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In direct ELISAs and Western blots, no cross-reactivity with recombinant human Spinesin is observed.
Reconstitute at 0.5 mg/mL in sterile PBS.
Spinesin, also known as Serine protease 22 (PRSS22), is a gene located on chromosome 16p11.2 that encodes a trypsin-like serine protease predominantly expressed in the brain and airway tissues. This protease is part of the large family of serine proteases, characterized by their involvement in a variety of physiological processes, including digestion, immune response, and cellular remodeling. In the nervous system, Spinesin is implicated in synaptic function and plasticity, with potential roles in modulating neural connectivity and communication. It is also involved in processing extracellular matrix components, which can influence cell adhesion and migration, contributing to tissue remodeling and repair processes. Dysregulation of Spinesin expression or activity may impact neural development and has been associated with certain neurological disorders. Research into Spinesin continues to explore its specific functions in the nervous system and its potential therapeutic applications in neurobiology and regenerative medicine.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MGC141886; MGC148044; Spinesin; Transmembrane protease serine 5
基因别名: spinesin; Tmprss5
UniProt ID: (Mouse) Q9ER04
Entrez Gene ID: (Mouse) 80893