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Invitrogen
Stargazin Polyclonal Antibody
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产品信息
PA1-4709
产品规格
种属反应
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to the C-terminal region of mouse CACNG2 conjugated to KLH
偶联物
形式
Liquid
浓度
0.25 mg/mL
纯化类型
Affinity chromatography
保存液
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with mouse based on 100% sequence homology.
In Western blot, PA1-4709 detects the ~36 kDa Stargazin protein.
靶标信息
Stargazin is a member of the transmembrane AMPAR regulatory proteins (TARP) family and is involved in glutamate receptor trafficking. It has been recently demonstrated that the interaction between stargazin and AMPA receptors is critical for the correct localization of the receptors at the synapse. Phosphorylation of the stargazin protein at Thr 321 by Protein Kinase A regulates its interaction with PSD-95 and synaptic targeting of AMPA receptors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CaV gamma 2; MGC123981; MGC138502; MGC138504; Neuronal voltage-gated calcium channel gamma-2 subunit; Stargazin; TARP; TARP gamma-2; Transmembrane AMPAR regulatory protein gamma-2; Voltage-dependent calcium channel gamma-2 subunit
基因别名: Cacng2; Ipr328; Stg
UniProt ID: (Rat) Q71RJ2
Entrez Gene ID: (Rat) 84347
neuromuscular junction development
transmission of nerve impulse
regulation of ion transmembrane transport
regulation of membrane potential
neurological system process
membrane depolarization
membrane hyperpolarization
calcium ion transmembrane transport
regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
