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Alomone Labs, LTD
Stomatin-like Protein 1 (extracellular) Polyclonal Antibody
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Stomatin-like Protein 1 (extracellular) Antibody (AIP-001-200UL) in WB
Western blot analysis of rat dorsal root ganglia lysates: - 1. Anti-Stomatin-like Protein 1 (extracellular) Antibody (#AIP-001), (1:500). 2. Anti-Stomatin-like Protein 1 (extracellular) Antibody , preincubated with Stomatin-like Protein 1 (extracellular) Blocking Peptide (#BLP-IP001).
产品信息
AIP-001-200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)RSGYRALPLGDFDR, corresponding to amino acid residues 4-17 of mouse STOML1, Extracellular, N-terminus
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
Stomatin-like protein 1 (STOML1) is encoded by the STOML1 gene located on chromosome 17 in humans. It is part of a family of five mammalian genes that encode peripheral membrane proteins involved in modulating ion channel functions. STOML1 is known to interact specifically with members of the acid-sensing ion channel (ASIC) family, influencing their proton sensitivity. These interactions help regulate ion transport and signaling pathways, which are critical for cellular homeostasis. In addition, STOML1 has been studied in the context of oral squamous cell carcinoma (OSCC), where it is often overexpressed along with STOML2, potentially affecting cancer progression. Structurally, STOML1 contains a stomatin domain which is crucial for its role in membrane association and ion channel modulation. Its expression in olfactory sensory neurons (OSNs) is comparatively lower than other family members, but it still contributes to the localization and functional integrity of related proteins in these cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EPB72-like 1; EPB72-like protein 1; Protein unc-24 homolog; SLP-1; stomatin (EBP72)-like 1; stomatin (EPB72)-like 1; stomatin-like 1; Stomatin-like protein 1; Stomatin-related protein; STORP
基因别名: 1810015E19Rik; AI847431; hUNC-24; MSTP019; RGD1559463; SLP-1; SLP1; STOML1; STORP; UNC24; WPB72
UniProt ID: (Human) Q9UBI4, (Mouse) Q8CI66
Entrez Gene ID: (Human) 9399, (Rat) 300748, (Mouse) 69106
