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Antibodies Inc
Synapsin-3 Monoclonal Antibody (L125/121), FL490
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产品信息
75-494-FL490
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
L125/121
抗原
Fusion protein amino acids 76-417 (actin-binding and synaptic-vesicle binding domains) of human Synapsin-III (accession number O14994) produced recombinantly in E. Coli.
偶联物
激发/发射光谱
491/515 nm
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Dry ice (international)
产品详细信息
For maximum recovery of product, centrifuge the vial prior to removing the cap.
靶标信息
This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. The protein encoded by this gene shares the synapsin family domain model, with domains A, C, and E exhibiting the highest degree of conservation. The protein contains a unique domain J, located between domains C and E. Based on this gene's localization to 22q12.3, a possible schizophrenia susceptibility locus, and the established neurobiological roles of the synapsins, this family member may represent a candidate gene for schizophrenia. The TIMP3 gene is located within an intron of this gene and is transcribed in the opposite direction.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cN28H9.2 (synapsin III); synapsin 3; Synapsin III; synapsin IIIa; Synapsin-3
基因别名: SYN3
UniProt ID: (Human) O14994, (Mouse) Q8JZP2, (Rat) O70441
Entrez Gene ID: (Human) 8224, (Mouse) 27204, (Rat) 29130
