Search
Invitrogen
Synaptotagmin 4 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
图: 1 / 3
Synaptotagmin 4 Antibody (PA5-104174) in ICC/IF
Immunofluorescent analysis of Synaptotagmin 4 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and Synaptotagmin 4 polyclonal antibody (Product # PA5-104174) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Ale... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-104174
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human SYT4(Accession Q9H2B2), corresponding to amino acid residues G74-K124.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total SYT4.
靶标信息
May be involved in Ca2+-dependent exocytosis of secretory vesicles through Ca2+ and phospholipid binding to the C2 domain or may serve as Ca2+ sensors in the process of vesicular trafficking and exocytosis. Plays a role in dendrite formation by melanocytes (PubMed:23999003).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: Synaptotagmin IV; Synaptotagmin-4; Synaptotagmin4; SytIV; unnamed protein product
基因别名: HsT1192; KIAA1342; SYT4
Entrez Gene ID: (Human) 6860
vesicle fusion
memory
positive regulation of glutamate secretion
regulation of dopamine secretion
vesicle-mediated transport
regulation of calcium ion-dependent exocytosis
regulation of endocytosis
regulation of vesicle fusion
negative regulation of catecholamine secretion
negative regulation of calcium ion-dependent exocytosis
positive regulation of calcium ion-dependent exocytosis
negative regulation of short-term neuronal synaptic plasticity
negative regulation of protein secretion
calcium-dependent activation of synaptic vesicle fusion
dense core granule cytoskeletal transport
regulation of trans-synaptic signaling by BDNF, modulating synaptic transmission
regulation of postsynaptic dense core vesicle exocytosis
negative regulation of secretion by cell
positive regulation of dendrite extension
positive regulation of dense core granule exocytosis
negative regulation of retrograde trans-synaptic signaling by neuropeptide
negative regulation of synaptic vesicle exocytosis
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
