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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: TASSLVVAPR CELTVWSRQG KAGKTHKFSA GTYPRLEEYR RGILGDWSNA ISALYCRCP
Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 71%.
Syncollin is a 134 amino acid, small peripheral membrane protein abundantly expressed in pancreatic acinar cells and is tightly associated with the lumenal side of the zymogen granule membrane. It contains intrachain disulfide bonds. Syncollin is also known to associate with lipid rafts in a cholesterol-dependent manner. In pancreatic acinar cells, syncollin helps in exocytosis and also plays a role in maturation and/or concentration of zymogens in zymogen granules. Reports suggest that syncollin may also have a pore-forming activity on membranes and regulate exocytosis insome exocrine tissues.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FLJ27441; Insulin synthesis-associated protein 1; Syncollin
基因别名: INSSA1; SYCN; SYL
Entrez Gene ID: (Human) 342898