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Invitrogen
Syndecan 4 Polyclonal Antibody
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Syndecan 4 Antibody (36-3100) in IHC (P)
Immunohistochemistry analysis of Syndecan-4 showing staining in the cytoplasm of paraffin-embedded human colon tissue (right) compared to a negative control without primary antibody (left). To expose target proteins, antigen retrieval was performed using 10mM sodium citrate (pH 6.0), microwaved for 8-15 min. Following antigen retrieval, tissues were blocked in 3% H2O2-methanol for 15 min at room temperature... View More
产品信息
36-3100
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human,
Mammal,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide derived from the middle region of the human Syndecan-4 protein.
偶联物
形式
Liquid
浓度
0.25 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.1% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Syndecans are type I integral membrane proteoglycans that are involved in cell-extracellular matrix adhesion and growth factor binding. Syndecan 1 is a matrix receptor which binds to Collagens, Fibronectin and Thrombospondin. Syndecan 1 and Syndecan 3 interact with MK (midkine), a growth/differentiation factor involved in embryogenesis. Syndecan 2 is highly expressed at areas of high morphogenetic activity, such as epithelial-mesenchymal interfaces and the prechondrogenic and preosteogenic mesenchymal condensations. Syndecan 4 functions cooperatively with integrins in the processes of cell spreading and focal adhesion assembly.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Amphiglycan; MGC22217; ryudocan amphiglycan; Ryudocan core protein; SYND4; syndecan 4 (amphiglycan, ryudocan); syndecan proteoglycan 4; Syndecan-4
基因别名: SDC4; SYND4
UniProt ID: (Human) P31431
Entrez Gene ID: (Human) 6385
retinoid metabolic process
ureteric bud development
neural tube closure
glycosaminoglycan biosynthetic process
glycosaminoglycan catabolic process
signal transduction
regulation of fibroblast migration
cell migration
glycosaminoglycan metabolic process
wound healing
positive regulation of protein kinase activity
positive regulation of stress fiber assembly
positive regulation of focal adhesion assembly
inner ear receptor stereocilium organization
positive regulation of exosomal secretion
positive regulation of extracellular exosome assembly
