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Invitrogen
Syntaxin 4 Polyclonal Antibody
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产品信息
PA5-44996
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the C-terminal of human STX4 (aa 231-280).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Peptide sequence: VEMQGEMINR IEKNILSSAD YVERGQEHVK TALENQKKAR KKKVLIAICV
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 91%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 93%
靶标信息
STX4 is a plasma membrane t-SNARE that mediates docking of transport vesicles.STX4 is necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. Together with STXB3 and VAMP2, STX4 may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes. STX4 may also play a role in docking of synaptic vesicles at presynaptic active zones.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Renal carcinoma antigen NY-REN-31; syntaxin 4A (placental); Syntaxin-4
基因别名: p35-2; STX4; STX4A
UniProt ID: (Human) Q12846
Entrez Gene ID: (Human) 6810
intracellular protein transport
post-Golgi vesicle-mediated transport
positive regulation of cell proliferation
regulation of exocytosis
positive regulation of cell migration
synaptic vesicle fusion to presynaptic active zone membrane
response to hydroperoxide
SNARE complex assembly
positive regulation of insulin secretion involved in cellular response to glucose stimulus
positive regulation of catalytic activity
positive regulation of eosinophil degranulation
positive regulation of cell adhesion
vesicle docking
organelle fusion
positive regulation of chemotaxis
positive regulation of immunoglobulin secretion
long-term synaptic potentiation
positive regulation of establishment of protein localization to plasma membrane
regulation of extrinsic apoptotic signaling pathway via death domain receptors
positive regulation of protein localization to plasma membrane
positive regulation of protein localization to cell surface
