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Abnova
TAF1 Monoclonal Antibody (1E11)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00006872-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
1E11
抗原
TAF1 (NP_004597, 1784 a.a. approximately 1893 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: RMLQENTRMD MENEESMMSY EGDGGEASHG LEDSNISYGS YEEPDPKSNT QDTSFSSIGG YEVSEEEEDE EEEEQRSGPS VLSQVHLSED EEDSEDFHSI AGDSDLDSDE
靶标信息
3-Phosphoglycerate dehydrogenase (PHGDH; EC 1.1.1.95) catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cell cycle gene 1 protein; cell cycle, G1 phase defect; complementation of cell cycle block, G1-to-S; TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa; TBP-associated factor 250 kDa; transcription factor TFIID p250 polypeptide
基因别名: BA2R; CCG1; CCGS; DYT3; DYT3/TAF1; KAT4; MRXS33; N-TAF1; NSCL2; OF; P250; TAF(II)250; TAF2A; TAFII-250; TAFII250; XDP
UniProt ID: (Human) P21675
Entrez Gene ID: (Human) 6872
RNA polymerase II core promoter sequence-specific DNA binding
RNA polymerase II general transcription initiation factor binding
transcription factor activity, core RNA polymerase I binding
p53 binding
DNA binding
histone acetyltransferase activity
protein kinase activity
protein serine/threonine kinase activity
protein binding
obsolete general RNA polymerase II transcription factor activity
kinase activity
ligand-dependent nuclear receptor binding
TBP-class protein binding
sequence-specific DNA binding
protein heterodimerization activity
H3K27me3 modified histone binding
RNA polymerase II sequence-specific DNA binding transcription factor binding
ubiquitin conjugating enzyme activity
peptide-lysine-N-acetyltransferase activity
protein serine kinase activity
histone H4K16ac reader activity
transcription regulator inhibitor activity
histone reader activity
acetyl-CoA binding
negative regulation of transcription from RNA polymerase II promoter
protein polyubiquitination
chromatin organization
chromatin remodeling
DNA-templated transcription, initiation
transcription initiation from RNA polymerase I promoter
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
ubiquitin-dependent protein catabolic process
cellular response to DNA damage stimulus
negative regulation of gene expression
midbrain development
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
cellular response to UV
mRNA transcription from RNA polymerase II promoter
positive regulation of transcription from RNA polymerase II promoter
protein autophosphorylation
protein stabilization
RNA polymerase II transcriptional preinitiation complex assembly
positive regulation of transcription initiation from RNA polymerase II promoter
cellular response to ATP
positive regulation of androgen receptor signaling pathway
regulation of signal transduction by p53 class mediator
negative regulation of signal transduction by p53 class mediator
regulation of cell cycle G1/S phase transition
negative regulation of protein autoubiquitination
negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
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