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Invitrogen
TAFA1 Polyclonal Antibody
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FIGURE: 1 / 1
TAFA1 Antibody (PA5-48071) in IHC (P)
Immunohistochemical analysis of TAFA1 in immersion fixed paraffin-embedded sections of human brain (cortex). Samples were incubated in TAFA1 polyclonal antibody (Product # PA5-48071) using a dilution of 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown) and counterstained with hematoxylin (blue). Lower panel shows a lack of labeling when primary ant... View More
Product Details
PA5-48071
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived recombinant human TAFA1/FAM19A1 Ser26-Thr133
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
In direct ELISAs, approximately 15% cross-reactivity with recombinant human (rh) TAFA3 and rhTAFA4 is observed, less than 10% cross-reactivity with rhTAFA2 is observed and less than 1% cross-reactivity with rhTAFA5 is observed.
Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.
Target Information
TAFA Chemokine Like Family Member 1 (TAFA1) is a gene located on chromosome 7q31.1, encoding a protein that is part of the FAM19A family, known for its role in modulating inflammation and neural development. TAFA1 is expressed in the brain where it influences brain-tissue homeostasis and neuronal signaling pathways. Functionally, TAFA1 acts as a chemokine-like protein, impacting the migration and adhesion of neuronal cells and contributing to neuroprotective activities. Its expression is implicated in maintaining neural network integrity and regulating processes such as neurogenesis and synaptic plasticity. Dysregulation of TAFA1 has been associated with neuroinflammatory conditions and neurodegenerative diseases, reflecting its importance in neural health and pathology. Research into TAFA1 aims to uncover its exact biological roles and potential as a therapeutic target in conditions involving disrupted cellular communication and inflammation in the nervous system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Chemokine-like protein TAFA-1; family with sequence similarity 19 (chemokine (C-C motif)-like), member A1
Gene Aliases: FAM19A1; TAFA-1; TAFA1
UniProt ID: (Human) Q7Z5A9
Entrez Gene ID: (Human) 407738
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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