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Invitrogen
TARC Polyclonal Antibody, Biotin, PeproTech®
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TARC Antibody (500-P97BT-25UG) in WB
Western Blot: To detect hTARC by Western Blot analysis TARC Polyclonal Antibody, Biotin (Product # 500-P97BT-500UG) can be used at a concentration of 0.1-0.2 µg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant hTARC is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
产品信息
500-P97BT-25UG
产品规格
种属反应
Human
宿主/亚型
Rabbit
分类
Polyclonal
类型
Antibody
抗原
E.coli-derived, 8.0 kDa Recombinant Human TARC
偶联物
形式
Lyophilized
浓度
0.1-1.0 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
no preservative
保存条件
-20°C
运输条件
Ambient
RRID
产品详细信息
AA Sequence of recombinant protein: ARGTNVGREC CLEYFKGAIP LRKLKTWYQT SEDCSRDAIV FVTVQGRAIC SDPNNKRVKN AVKYLQSLER S.
Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human TARC (CCL17). Anti-Human TARC (CCL17)-specific antibody was purified by affinity chromatography and then biotinylated.
Sandwich ELISA: To detect hTARC by sandwich ELISA (using 100 µL/well antibody solution) a concentration of 0.25-1.0 µg/mL of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human TARC (500-P97) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant hTARC.
Western Blot: To detect hTARC by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 µg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant hTARC is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
500-P97BT-1MG will be provided as 2 x 500 µg
靶标信息
TARC ligand (CCL17) belongs to the CC chemokine family. It is a small cytokine and the gene is located on q arm of chromosome 16, in humans, along with other chemokines. TARC specifically binds to T-cells and interacts with chemokine receptors CCR4 and CCR8. It plays an important role in T cell development in thymus as well as in trafficking and activation of mature T cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C-C motif chemokine; C-C motif chemokine 17; CC chemokine TARC; chemokine (C-C motif) ligand 17; small inducible cytokine subfamily A (Cys-Cys), member 17; Small-inducible cytokine A17; T cell-directed CC chemokine; Thymus and activation-regulated chemokine
基因别名: A-152E5.3; ABCD-2; CCL17; SCYA17; TARC
UniProt ID: (Human) Q92583
Entrez Gene ID: (Human) 6361
monocyte chemotaxis
chemotaxis
inflammatory response
G-protein coupled receptor signaling pathway
cell-cell signaling
multicellular organism development
neutrophil chemotaxis
positive regulation of GTPase activity
negative regulation of myoblast differentiation
lymphocyte chemotaxis
chemokine-mediated signaling pathway
positive regulation of ERK1 and ERK2 cascade
cellular response to interferon-gamma
cellular response to interleukin-1
cellular response to tumor necrosis factor
