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Invitrogen
TAS2R16 Polyclonal Antibody
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产品信息
PA5-102251
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human TAS2R16(Accession Q9NYV7), corresponding to amino acid residues I142-F192.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total TAS2R16.
靶标信息
This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily. These family members are specifically expressed by taste receptor cells of the tongue and palate epithelia. Each of these apparently intronless genes encodes a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes in chromosome 7 and is genetically linked to loci that influence bitter perception. Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. Expressed in a subset of gustducin-positive taste receptor cells of the tongue. The Lys-172 polymorphism in TAS2R16 is associated with genetic susceptibility to alcoholism. Confers bitter perception of salicin to non-taster mice.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: candidate taste receptor T2R16; T2R16; Taste receptor type 2 member 16; taste receptor, type 2, member 16
基因别名: T2R16; TAS2R16
UniProt ID: (Human) Q9NYV7
Entrez Gene ID: (Human) 50833
