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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Predicted to react with Mouse and Rat samples.
This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by taste receptor cells of the tongue and palate epithelia. These apparently intronless genes encode a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes in chromosome 7 and is genetically linked to loci that influence bitter perception. Gustducin-coupled receptor for denatonium and N(6)-propyl-2-thiouracil implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: bitter taste receptor T2R16; candidate taste receptor T2R8; MGC163311; T2R16; T2R20; T2R4; T2R8; tas2r4 {ECO:0000250|UniProtKB:Q9JKT3}; taste receptor T2R8; Taste receptor type 2 member 108; Taste receptor type 2 member 20; Taste receptor type 2 member 4; Taste receptor type 2 member 8
Gene Aliases: mGR08; mt2r8; T2R108; T2R16; T2r20; T2r8; Tas2r108; TAS2R4; Tas2r8
UniProt ID: (Mouse) Q9JKT3, (Rat) Q67ET0
Entrez Gene ID: (Mouse) 57253, (Rat) 554302
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