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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of total TAS2R4.
This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by taste receptor cells of the tongue and palate epithelia. These apparently intronless genes encode a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes in chromosome 7 and is genetically linked to loci that influence bitter perception. Gustducin-coupled receptor for denatonium and N(6)-propyl-2-thiouracil implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: bitter taste receptor T2R16; candidate taste receptor T2R8; MGC163311; T2R16; T2R20; T2R4; T2R8; tas2r4 {ECO:0000250|UniProtKB:Q9JKT3}; taste receptor T2R8; Taste receptor type 2 member 108; Taste receptor type 2 member 20; Taste receptor type 2 member 4; Taste receptor type 2 member 8
基因别名: mGR08; mt2r8; T2R108; T2R16; T2r20; T2r8; Tas2r108; TAS2R4; Tas2r8
UniProt ID: (Mouse) Q9JKT3, (Rat) Q67ET0
Entrez Gene ID: (Mouse) 57253, (Rat) 554302