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Antibody detects endogenous levels of total TAS2R46.
Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MGC134865; T2R46; T2R54; TAS2R47; Taste receptor type 2 member 46; Taste receptor type 2 member 54; taste receptor, type 2, member 46
基因别名: T2R46; T2R54; TAS2R46
UniProt ID: (Human) P59540
Entrez Gene ID: (Human) 259292