Search
Search
Abnova
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MSITSDEVNF LVYRYLQESG FSHSAFTFGI ESHISQSNIN GTLVPPAALI SILQKGLQYV EAEISINEDG TVFDGRPIES LSLIDAVMPD VVQTRQQAFR EKLAQQQASA AAAAAAATAA ATAATTTSAG VSHQNPSKNR EATVNGEENR AHSVNNHAKP MEIDGEVEIP SSKATVLRGH ESEVFICAWN PVSDLLASGS GDSTARIWNL NENSNGGSTQ LVLRHCIREG GHDVPSNKDV TSLDWNTNGT LLATGSYDGF ARIWTEDGNL ASTLGQHKGP IFALKWNRKG NYILSAGVDK TTIIWDAHTG EAKQQFPFHS APALDVDWQN NTTFASCSTD MCIHVCRLGC DRPVKTFQGH TNEVNAIKWD PSGMLLASCS DDMTLKIWSM KQEVCIHDLQ AHNKEIYTIK WSPTGPATSN PNSNIMLASA SFDSTVRLWD IERGVCTHTL TKHQEPVYSV AFSPDGKYLA SGSFDKCVHI WNTQSGNLVH SYRGTGGIFE VCWNARGDKV GASASDGSVC VLDLRK
The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: F-box-like/WD repeat-containing protein TBL1X; SMAP55; Transducin beta-like protein 1X; Transducin-beta-like protein 1, X-linked
基因别名: EBI; SMAP55; TBL1; TBL1X
UniProt ID: (Human) O60907
Entrez Gene ID: (Human) 6907