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Invitrogen
TBL3 Polyclonal Antibody
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TBL3 Antibody (PA5-35993) in ICC/IF
TBL3 Polyclonal Antibody detects TBL3 protein at nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: TBL3 protein stained by TBL3 Polyclonal Antibody (Product # PA5-35993) diluted at 1:200. Blue: Hoechst 33342 staining. Scale bar = 10 µm.
产品信息
PA5-35993
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human TBL3. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.71 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
产品详细信息
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Predicted reactivity: Mouse (91%), Rat (92%), Bovine (96%).
靶标信息
WNK is a serine/threonine kinase that plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Also, acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A, SCNN1B, SCNN1D, and SGK1. WNK localizes to a segment of kidney involved in salt, potassium, and pH homeostasis, the distal nephron. Mutations in the WNK gene result in Pseudohypaldosteronism and Neuropathy.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: transducin (beta)-like 3; Transducin beta-like protein 3; WD repeat-containing protein SAZD; WD-repeat protein SAZD
基因别名: SAZD; TBL3; UTP13
UniProt ID: (Human) Q12788
Entrez Gene ID: (Human) 10607
