Search Thermo Fisher Scientific
图: 1 / 1
Positive Samples: MCF7; Cellular Location: Nucleus
Immunogen sequence: GSLSRSPFLG SARPRLRFSP YQIPVTIPPS TSLLTTGLAS EGSKAAGGNS REPSPLPELA LRKVGAPSRG ALSPSGSAKE AANELQSIQR LVSGLESQRA LSPGRESPK
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. Transcript heterogeneity due to alternative polyadenylation has been noted for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FLJ10169; T-box protein 2; T-box transcription factor TBX2
基因别名: TBX2
UniProt ID: (Human) Q13207, (Mouse) Q60707
Entrez Gene ID: (Human) 6909, (Mouse) 21385, (Rat) 303398
分子生物学功能: Rel homology transcription factor