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TCEA1 is necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. TCEA1 has a role in suppression of transient pausing, which is the most important contribution of TCEA1 to elongation from a stall position. TCEA1 fuse to PLAG1 protein which is overexpressed in epithelial, myoepithelial, and mesenchymal-like tumor cells in tumors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: transcription elongation factor A (SII), 1; Transcription elongation factor A protein 1; Transcription elongation factor S-II protein 1; Transcription elongation factor TFIIS.o; transcription factor IIS
基因别名: GTF2S; S-II; SII; TCEA; TCEA1; Tceat; TF2S; TFIIS
UniProt ID: (Human) P23193, (Mouse) P10711, (Rat) Q4KLL0
Entrez Gene ID: (Human) 6917, (Mouse) 21399, (Rat) 362479
分子生物学功能: general transcription factor