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Bethyl Laboratories
TCEB1 Polyclonal Antibody
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TCEB1 Antibody (A304-787A) in IHC (P)
Detection of human TCEB1 by immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-TCEB1 (Product # A304-787A) (Lot 1) used at a dilution of 1:1,000 (1 µg/mL). Detection: DAB. Counterstain: IHC Hematoxylin (blue).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
A304-787A
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 1 to 50 of Human Transcription elongation factor B polypeptide 1.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
phosphate/tris citrate, pH 7-8
内含物
0.09% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Based on 100% sequence identity, this antibody is predicted to react with Rat and Bovine
靶标信息
TCEB1 is known as protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: elongin 15 kDa subunit; RNA polymerase II transcription factor SIII subunit C; SIII p15; stromal membrane-associated protein SMAP1B homolog; transcription elongation factor B (SIII), polypeptide 1; transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C); transcription elongation factor B polypeptide 1; transcription elongation factor B subunit 1; unnamed protein product
基因别名: 2610043E24Rik; 2610301I15Rik; SIII; TCEB1
UniProt ID: (Human) Q15369, (Mouse) P83940
Entrez Gene ID: (Human) 6921, (Mouse) 67923
transcription initiation from RNA polymerase II promoter
ubiquitin-dependent protein catabolic process
protein ubiquitination
ubiquitin-dependent protein catabolic process via the C-end degron rule pathway
target-directed miRNA degradation
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription from RNA polymerase II promoter
proteasome-mediated ubiquitin-dependent protein catabolic process
ribosome-associated ubiquitin-dependent protein catabolic process
negative regulation of DNA-dependent DNA replication
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