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Abnova
TCF12 Monoclonal Antibody (2E9)
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产品信息
H00006938-M01
产品规格
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
2E9
抗原
TCF12 (NP_996919, 364 a.a. approximately 453 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
See Label
规格
100 µg
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: VGSPSPLTGT SQWPRPGGQA PSSPSYENSL HSLKNRVEQQ LHEHLQDAMS FLKDVCEQSR MEDRLDRLDD AIHVLRNHAV GPSTSLPAGH
靶标信息
TCF12, also known as HTF4, is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. TCF12 is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. TCF12, in combination with E2A, is required to block thymocyte proliferation prior to pre-TCR expression and is critical for proper T cell differentiation. Recent reports have shown that TCF12 is also a critical factor required for the development of invariant natural killer T cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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