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Invitrogen
TDRD6 Polyclonal Antibody
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产品信息
PA5-140337
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: INSSYKELKL LQSLTKTNLV TQYQDSVGNK NSQVFPLTTE KKEEISAETP LKTARVEATL SERKIGDSCD KDLPLKFCEF PQKTI
Highest antigen sequence indentity to the following orthologs: Rat - 53%, Mouse - 54%.
靶标信息
Tudor domain-containing protein involved in germ cell development, more specifically the formation of chromatoid body (during spermiogenesis), Balbiani body (during oogenesis), germ plasm (upon fertilization), and for proper miRNA expression and spliceosome maturation. Essential for RNA-dependent helicase UPF1 localization to chromatoid body, for UPF1-UPF2 and UPF1-DDX4 interactions which are required for mRNA degradation, using the extended 3' UTR-triggered nonsense-mediated mRNA decay (NMD) pathway. Involved in spliceosome maturation and mRNA splicing in prophase I spermatocytes through interaction with arginine N-methyltransferase PRMT5 and symmetrically arginine dimethylated SNRPB (small nuclear ribonucleoprotein-associated protein).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Antigen NY-CO-45; Cancer/testis antigen 41.2; CT41.2; SPATA36; spermatogenesis associated 36; Tudor Domain Containing 6; Tudor domain-containing protein 6; tudor repeat 2
基因别名: bA446F17.4; CT41.2; NY-CO-45; SPATA36; TDR2; TDRD6
UniProt ID: (Human) O60522
Entrez Gene ID: (Human) 221400
