Search
Invitrogen
TET3 Recombinant Rabbit Monoclonal Antibody (HL2463)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
图: 1 / 4
TET3 Antibody (MA5-56893) in IHC (P)
Immunohistochemistry (Paraffin) analysis of TET3 stained by TET3 Recombinant Monoclonal Antibody (Product # MA5-56893). TET3 antibody detects TET3 protein on Paraffin-embedded mouse lung and colon diluted at 1:100. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-56893
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
HL2463
抗原
Recombinant fragment of human TET3.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Dry ice (international)
RRID
靶标信息
TET3, a member of the ten-eleven-translocation (TET) family of genes, is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine and is most abundantly expressed in hematopoietic cells. Unlike the related TET2 protein, mutations in TET3 have not been observed in any myeloid malignancies. TET3 has been shown to be involved in the demethylation of zygotic DNA before the first mitosis and has been suggested to be involved in the epigenetic reprogramming of the zygotic paternal DNA following natural fertilization and may also contribute to somatic cell nuclear reprogramming during animal cloning.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: astrotactin-2-like; KIAA0401; methylcytosine dioxygenase; MGC22014; probable methylcytosine dioxygenase TET3; putative methylcytosine dioxygenase; ten-eleven translocation 3; tet oncogene family member 3; unnamed protein product
基因别名: B430006D22Rik; BEFAHRS; D230004J03Rik; hCG_40738
UniProt ID: (Human) O43151, (Mouse) Q8BG87
Entrez Gene ID: (Human) 200424, (Rat) 680576, (Mouse) 194388
RNA polymerase II core promoter proximal region sequence-specific DNA binding
DNA binding
protein binding
zinc ion binding
methyl-CpG binding
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
methylcytosine dioxygenase activity
protein O-linked glycosylation
biological_process
regulation of gene expression
regulation of gene expression, epigenetic
hypomethylation of CpG island
DNA demethylation of male pronucleus
positive regulation of transcription from RNA polymerase II promoter
chromosomal 5-methylcytosine DNA demethylation pathway
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
