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Invitrogen
TET3 Recombinant Rabbit Monoclonal Antibody (HL2463)
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TET3 Antibody (MA5-56893) in IHC (P)
Immunohistochemistry (Paraffin) analysis of TET3 stained by TET3 Recombinant Monoclonal Antibody (Product # MA5-56893). TET3 antibody detects TET3 protein on Paraffin-embedded mouse lung and colon diluted at 1:100. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.
产品信息
MA5-56893
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
HL2463
抗原
Recombinant fragment of human TET3.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Dry ice (international)
RRID
靶标信息
TET3, a member of the ten-eleven-translocation (TET) family of genes, is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine and is most abundantly expressed in hematopoietic cells. Unlike the related TET2 protein, mutations in TET3 have not been observed in any myeloid malignancies. TET3 has been shown to be involved in the demethylation of zygotic DNA before the first mitosis and has been suggested to be involved in the epigenetic reprogramming of the zygotic paternal DNA following natural fertilization and may also contribute to somatic cell nuclear reprogramming during animal cloning.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Methylcytosine dioxygenase TET3; MGC22014; probable methylcytosine dioxygenase TET3; putative methylcytosine dioxygenase; Tet methylcytosine deoxygenase 3 isoform; tet methylcytosine dioxygenase 3; tet oncogene family member 3
基因别名: B430006D22Rik; BC037432; D230004J03Rik; hCG_40738; KIAA0401; TET3
UniProt ID: (Human) O43151, (Mouse) Q8BG87
Entrez Gene ID: (Human) 200424, (Rat) 680576, (Mouse) 194388
