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Invitrogen
TFAP4 Polyclonal Antibody
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Product Details
PA5-95836
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 200-338 of human TFAP4 (NP_003214.1).
Conjugate
Form
Liquid
Concentration
2.6 mg/mL
Amount
260 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Cellular Location: Nucleus
Immunogen sequence: QQEQVRLLHQ EKLEREQQQL RTQLLPPPAP THHPTVIVPA PPPPPSHHIN VVTMGPSSVI NSVSTSRQNL DTIVQAIQHI EGTQEKQELE EEQRRAVIVK PVRSCPEAPT SDTASDSEAS DSDAMDQSRE EPSGDGELP
Target Information
Transcription factors of the basic helix-loop-helix-zipper(bHLH-ZIP) family contain a basic domain, which is used for DNA binding, and HLH and ZIP domains, which are used for oligomerization. Transcription factor AP4 activates both viral and cellular genes by binding to the symmetrical DNA sequence CAGCTG.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Activating enhancer-binding protein 4; basic helix-loop-helix DNA-binding protein; bHLHc41; Class C basic helix-loop-helix protein 41; TFAP4; Transcription factor AP-4; transcription factor AP-4 (activating enhancer binding protein 4); transcription factor AP4
Gene Aliases: AP-4; BHLHC41; Tcfap4; TFAP4
UniProt ID: (Human) Q01664
Entrez Gene ID: (Human) 7023, (Rat) 360482
transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
protein binding
protein homodimerization activity
histone deacetylase binding
sequence-specific DNA binding
protein dimerization activity
E-box binding
sequence-specific double-stranded DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
transcription coactivator activity
transcription regulatory region DNA binding
protein heterodimerization activity
DNA-binding transcription factor
regulation of transcription from RNA polymerase II promoter
negative regulation of cell proliferation
negative regulation of gene expression
DNA damage response, signal transduction by p53 class mediator
positive regulation of apoptotic process
negative regulation of DNA binding
negative regulation by host of viral transcription
positive regulation by host of viral transcription
negative regulation of cyclin-dependent protein serine/threonine kinase activity
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
protein-containing complex assembly
cellular response to dexamethasone stimulus
regulation of mitotic cell cycle phase transition
transcription from RNA polymerase II promoter
protein complex assembly
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
negative regulation of cell cycle arrest
positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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