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Invitrogen
TFAP4 Polyclonal Antibody
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产品信息
PA5-95836
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 200-338 of human TFAP4 (NP_003214.1).
偶联物
形式
Liquid
浓度
2.6 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Cellular Location: Nucleus
Immunogen sequence: QQEQVRLLHQ EKLEREQQQL RTQLLPPPAP THHPTVIVPA PPPPPSHHIN VVTMGPSSVI NSVSTSRQNL DTIVQAIQHI EGTQEKQELE EEQRRAVIVK PVRSCPEAPT SDTASDSEAS DSDAMDQSRE EPSGDGELP
靶标信息
Transcription factors of the basic helix-loop-helix-zipper(bHLH-ZIP) family contain a basic domain, which is used for DNA binding, and HLH and ZIP domains, which are used for oligomerization. Transcription factor AP4 activates both viral and cellular genes by binding to the symmetrical DNA sequence CAGCTG.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Activating enhancer-binding protein 4; bHLHc41; Class C basic helix-loop-helix protein 41; Transcription factor AP-4; transcription factor AP-4 (activating enhancer binding protein 4); transcription factor AP-4 (activating enhancer-binding protein 4); transcription factor AP4
基因别名: AP-4; BHLHC41; Tcfap4; TFAP4
UniProt ID: (Human) Q01664
Entrez Gene ID: (Human) 7023, (Rat) 360482
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
transcription coactivator activity
protein binding
protein homodimerization activity
histone deacetylase binding
sequence-specific DNA binding
transcription regulatory region DNA binding
protein heterodimerization activity
E-box binding
transcription factor activity, sequence-specific DNA binding
DNA-binding transcription factor
transcription from RNA polymerase II promoter
protein complex assembly
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
negative regulation of cell proliferation
positive regulation of apoptotic process
negative regulation of DNA binding
negative regulation by host of viral transcription
positive regulation by host of viral transcription
negative regulation of cyclin-dependent protein serine/threonine kinase activity
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of cell cycle arrest
cellular response to dexamethasone stimulus
positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
regulation of transcription from RNA polymerase II promoter
negative regulation of gene expression
