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Abnova
TFAP4 Monoclonal Antibody (8G6)
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产品信息
H00007023-M05
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
8G6
抗原
TFAP4 (NP_003214, 93 a.a. approximately 192 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.8 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: AEYIFSLEQE KTRLLQQNTQ LKRFIQELSG SSPKRRRAED KDEGIGSPDI WEDEKAEDLR REMIELRQQL DKERSVRMML EEQVRSLEAH MYPEKLKVIA
靶标信息
Transcription factors of the basic helix-loop-helix-zipper(bHLH-ZIP) family contain a basic domain, which is used for DNA binding, and HLH and ZIP domains, which are used for oligomerization. Transcription factor AP4 activates both viral and cellular genes by binding to the symmetrical DNA sequence CAGCTG.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Activating enhancer-binding protein 4; bHLHc41; Class C basic helix-loop-helix protein 41; Transcription factor AP-4; transcription factor AP-4 (activating enhancer-binding protein 4)
基因别名: AP-4; BHLHC41; TFAP4
UniProt ID: (Human) Q01664
Entrez Gene ID: (Human) 7023
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
transcription coactivator activity
protein binding
protein homodimerization activity
histone deacetylase binding
sequence-specific DNA binding
transcription regulatory region DNA binding
protein heterodimerization activity
E-box binding
DNA-binding transcription factor
transcription from RNA polymerase II promoter
protein complex assembly
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
negative regulation of cell proliferation
positive regulation of apoptotic process
negative regulation of DNA binding
negative regulation by host of viral transcription
positive regulation by host of viral transcription
negative regulation of cyclin-dependent protein serine/threonine kinase activity
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of cell cycle arrest
cellular response to dexamethasone stimulus
positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
