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TFIIIC mediates tRNA and 5S RNA gene activation by binding to intragenic promoter elements. Upstream of the transcription start site, TFIIIC assembles the initiation complex TFIIIB-TFIIIC-tDNA, which is sufficient for RNA polymerase III recruitment and function. Part of the tauB domain of TFIIIC that binds boxB DNA promoter sites of tRNA and similar genes. TFC3 is essential for cell viability. Cooperates with TFC6 in DNA binding.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: TFIIIC 138 kDa subunit; Transcription factor C subunit 3; Transcription factor tau 138 kDa subunit; TSV115
基因别名: FUN24; TFC3; TSV115; YAL001C
UniProt ID: (Baker's yeast) P34111
Entrez Gene ID: (Baker's yeast) 851262