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Abnova
TFG Polyclonal Antibody, MaxPab™
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产品信息
H00010342-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
TFG (AAH09241, 1 a.a. approximately 400 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MNGQLDLSGK LIIKAQLGED IRRIPIHNED ITYDELVLMM QRVFRGKLLS NDEVTIKYKD EDGDLITIFD SSDLSFAIQC SRILKLTLFV NGQPRPLESS QVKYLRRELI ELRNKVNRLL DSLEPPGEPG PSTNIPENDT VDGREEKSAS DSSGKQSTQV MAASMSAFDP LKNQDEINKN VMSAFGLTDD QVSGPPSAPA EDRSGTPDSI ASSSSAAHPP GVQPQQPPYT GAQTQAGQIE GQMYQQYQQQ AGYGAQQPQA PPQQPQQYGI QYSASYSQQT GPQQPQQFQG YGQQPTSQAP APAFSGQPQQ LPAQPPQQYQ ASNYPAQTYT AQTSQPTNYT VAPASQPGMA PSQPGAYQPR PGFTSLPGST MTPPPSGPNP YARNRPPFGQ GYTQPGPGYR
靶标信息
TFG protein, a recently identified novel protein, is a human homolog of mouse TFG protein. It contains an N-terminal coiled-coil structure, a SPYGQ-rich region followed by octicosapeptide repeats. Research shows that TFG can modulate SHP-1 activity and is a novel member of the NF-kB pathway. The physiological functions of this protein remain largely elusive, but TFG is thought to function by associating with other proteins, including TANK and NEMO. TFG was first identified as a partner of NTRK1 and is involved in generating the thyroid TRK-T3 oncogene, as well as oncogenic rearrangements with ALK in anaplastic lymphoma and NOR1 in mixoid chondrosarcoma.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Protein TFG; TRK-fused gene protein; TRKT3 oncogene
基因别名: HMSNP; SPG57; TF6; TFG; TRKT3
UniProt ID: (Human) Q92734
Entrez Gene ID: (Human) 10342
