TGF-beta (Transforming Growth Factor beta) Monoclonal Antibody (TGFB/510)

antigen binding type II transforming growth factor beta receptor binding protein binding growth factor activity type I transforming growth factor beta receptor binding type III transforming growth factor beta receptor binding beta-amyloid binding receptor binding transforming growth factor beta receptor binding protein homodimerization activity glycoprotein binding cytokine activity enzyme binding protein heterodimerization activity protein N-terminus binding receptor signaling protein serine/threonine kinase activity identical protein binding transforming growth factor beta binding growth factor

MAPK cascade epithelial to mesenchymal transition negative regulation of protein phosphorylation positive regulation of protein phosphorylation chondrocyte differentiation hematopoietic progenitor cell differentiation protein export from nucleus ATP biosynthetic process phosphate-containing compound metabolic process inflammatory response cell cycle arrest mitotic cell cycle checkpoint epidermal growth factor receptor signaling pathway transforming growth factor beta receptor signaling pathway common-partner SMAD protein phosphorylation SMAD protein complex assembly salivary gland morphogenesis positive regulation of cell proliferation negative regulation of cell proliferation response to wounding positive regulation of gene expression negative regulation of gene expression positive regulation of epithelial to mesenchymal transition positive regulation of fibroblast migration positive regulation of peptidyl-threonine phosphorylation positive regulation of pathway-restricted SMAD protein phosphorylation negative regulation of macrophage cytokine production positive regulation of microglia differentiation cell migration regulation of transforming growth factor beta receptor signaling pathway negative regulation of cell-cell adhesion hyaluronan catabolic process negative regulation of cell growth positive regulation of cell migration positive regulation of bone mineralization membrane protein intracellular domain proteolysis positive regulation of protein complex assembly lipopolysaccharide-mediated signaling pathway positive regulation of cellular protein metabolic process response to estradiol response to progesterone positive regulation of interleukin-17 production receptor catabolic process positive regulation of superoxide anion generation positive regulation of collagen biosynthetic process positive regulation of peptidyl-serine phosphorylation positive regulation of protein dephosphorylation positive regulation of protein import into nucleus positive regulation of MAP kinase activity protein kinase B signaling positive regulation of blood vessel endothelial cell migration negative regulation of blood vessel endothelial cell migration positive regulation of phosphatidylinositol 3-kinase activity ossification involved in bone remodeling cell-cell junction organization negative regulation of fat cell differentiation negative regulation of myoblast differentiation negative regulation of cell cycle negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated negative regulation of mitotic cell cycle positive regulation of transcription from RNA polymerase II promoter positive regulation of isotype switching to IgA isotypes negative regulation of skeletal muscle tissue development negative regulation of epithelial cell proliferation positive regulation of protein secretion positive regulation of chemotaxis positive regulation of cell division positive regulation of protein kinase B signaling pathway-restricted SMAD protein phosphorylation regulation of SMAD protein import into nucleus positive regulation of SMAD protein import into nucleus positive regulation of ERK1 and ERK2 cascade response to cholesterol cellular response to organic cyclic compound cellular response to transforming growth factor beta stimulus extracellular matrix assembly extrinsic apoptotic signaling pathway negative regulation of hyaluronan biosynthetic process positive regulation of NAD+ ADP-ribosyltransferase activity positive regulation of transcription regulatory region DNA binding protein phosphorylation regulation of striated muscle tissue development positive regulation of mammary gland epithelial cell proliferation regulation of protein import into nucleus positive regulation of fibroblast proliferation lymph node development regulation of binding regulation of DNA binding positive regulation of transdifferentiation cell morphogenesis eye development hair follicle development heart morphogenesis heart development cell death glial cell migration cardioblast differentiation positive regulation of epithelial cell migration negative regulation of alkaline phosphatase activity positive regulation of phosphatidylinositol 3-kinase signaling signal transduction by protein phosphorylation collagen fibril organization positive regulation of cell growth activation of protein kinase activity positive regulation of stress-activated MAPK cascade regulation of transforming growth factor beta2 production positive regulation of cell adhesion mediated by integrin response to drug positive regulation of neuron apoptotic process positive regulation of integrin biosynthetic process positive regulation of ossification positive regulation of heart contraction embryonic digestive tract development positive regulation of catagen positive regulation of cardioblast differentiation cardiac muscle cell proliferation cardiac epithelial to mesenchymal transition SMAD protein signal transduction protein import into nucleus, translocation negative regulation of transcription from RNA polymerase II promoter regulation of cell growth ureteric bud development response to hypoxia morphogenesis of a branching structure cell activation regulation of sodium ion transport adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains tolerance induction to self antigen cellular calcium ion homeostasis SMAD protein import into nucleus negative regulation of neuroblast proliferation endoderm development female pregnancy aging negative regulation of DNA replication cell proliferation germ cell migration response to radiation response to glucose defense response to fungus, incompatible interaction response to organic substance response to organic cyclic compound cell growth evasion or tolerance of host defenses by virus T cell differentiation negative regulation of ossification lung development mammary gland development positive regulation of histone deacetylation organ regeneration positive regulation of exit from mitosis mononuclear cell proliferation response to vitamin D response to laminar fluid shear stress positive regulation of histone acetylation wound healing T cell activation regulation of cell proliferation negative regulation of T cell proliferation positive regulation of odontogenesis myelination myeloid dendritic cell differentiation T cell homeostasis positive regulation of apoptotic process regulation of MAPK cascade regulatory T cell differentiation digestive tract development inner ear development positive regulation of epithelial cell proliferation negative regulation of phagocytosis negative regulation of immune response negative regulation of T cell activation positive regulation of NF-kappaB transcription factor activity positive regulation of smooth muscle cell differentiation negative regulation of release of sequestered calcium ion into cytosol face morphogenesis frontal suture morphogenesis mammary gland branching involved in thelarche branch elongation involved in mammary gland duct branching regulation of branching involved in mammary gland duct morphogenesis negative regulation of gene silencing by miRNA regulation of cartilage development lens fiber cell differentiation positive regulation of cell cycle arrest cellular response to growth factor stimulus cellular response to dexamethasone stimulus positive regulation of branching involved in ureteric bud morphogenesis positive regulation of protein localization to nucleus regulation of actin cytoskeleton reorganization regulation of miRNA metabolic process skeletal system development CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment defense response Notch signaling pathway skeletal muscle tissue development organ morphogenesis regulation of gene expression regulation of interleukin-23 production negative regulation of interleukin-17 production regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation growth regulation of apoptotic process cell development T-helper 17 cell lineage commitment cartilage condensation blood vessel development blood vessel remodeling outflow tract morphogenesis heart valve morphogenesis cardiac left ventricle morphogenesis cardiac right ventricle morphogenesis axon guidance hemopoiesis extracellular matrix organization hair follicle morphogenesis intracellular signal transduction dopamine biosynthetic process catagen negative regulation of apoptotic process response to estrogen negative regulation of keratinocyte differentiation positive regulation of cell cycle somatic stem cell division neuron fate commitment neuron development embryonic neurocranium morphogenesis ventricular septum morphogenesis negative regulation of cartilage development positive regulation of activation-induced cell death of T cells regulation of extracellular matrix organization positive regulation of extrinsic apoptotic signaling pathway in absence of ligand kidney development response to cold response to organonitrogen compound neutrophil chemotaxis thyroid gland development hindbrain development pancreas development response to retinoic acid response to cytokine positive regulation of immune response regulation of complement-dependent cytotoxicity activation of MAPK activity in utero embryonic development negative regulation of transforming growth factor beta receptor signaling pathway regulation of epithelial cell differentiation negative regulation of neuron apoptotic process regulation of endothelial cell differentiation positive regulation of DNA replication lung alveolus development regulation of epithelial cell proliferation positive regulation of filopodium assembly palate development detection of hypoxia embryo development