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Recommended positive controls: A431, H1299, HeLa.
Predicted reactivity: Rat (100%), Rhesus Monkey (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene is a DNA-binding homeobox protein and a transcriptional repressor, which appears to repress transcription by recruiting histone deacetylases to TGF beta-responsive genes. This gene is amplified and over-expressed in some ovarian cancers. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. Read-through transcription also exists between this gene and the neighboring downstream C20orf24 gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 5'-TG-3' interacting factor 2; 5'-TG-3'-interacting factor 2; Homeobox protein TGIF2; OTTHUMP00000030849; TGF(beta)-induced transcription factor 2; TGF-beta-induced transcription factor 2; TGFB-induced factor 2; TGFB-induced factor 2 (TALE family homeobox); TGFB-induced factor homeobox 2; transcription growth factor-beta-induced factor 2
基因别名: TGIF2
UniProt ID: (Human) Q9GZN2
Entrez Gene ID: (Human) 60436