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Fabgennix
THAP1 Polyclonal Antibody, FITC
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产品信息
THAP1-FITC
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide taken within amino acid region 150-210 on human THAP domain-containing protein 1.
偶联物
激发/发射光谱
498/517 nm
查看光谱
形式
Liquid
浓度
0.5-1.5 mg/mL
纯化类型
Affinity chromatography
保存液
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20°C, store in dark
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes, including RRM1. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. May also have pro-apoptopic activity by potentiating both serum-withdrawal and TNF-induced apoptosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 4833431A01Rik; nuclear proapoptotic factor; THAP domain containing, apoptosis associated protein 1; THAP domain protein 1; THAP domain-containing apoptosis-associated protein 1; THAP domain-containing protein 1
基因别名: 4833431A01Rik; AW490810; DYT6; THAP1
UniProt ID: (Human) Q9NVV9, (Mouse) Q8CHW1, (Rat) Q5U208
Entrez Gene ID: (Human) 55145, (Mouse) 73754, (Rat) 306547
