Search
Invitrogen
THRA Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
产品信息
PA5-18777
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide sequence (KEEMIRSLQQRP) corresponding to the internal amino acids of THRA (aa 147-159).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with bovine, canine, mouse, porcine and rat based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.
靶标信息
The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: c-erbA protooncogene; c-erbA-1; c-erbA-alpha; cerbA protein; cerbAalpha; E ERB-T-1; EAR-7; ERBA ALPHA; ERBA related 7; ERBA-related 7; MGC000261; MGC43240; Nuclear receptor subfamily 1 group A member 1; Oncogene ERBA; THRA; Thyroid hormone receptor alpha; thyroid hormone receptor alpha 1; thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian); TR; TR alpha 1+2; triiodothyronine receptor; unnamed protein product; V-erbA-related protein 7
基因别名: AR7; c-erbA; c-ERBA-1; CHNG6; EAR7; ERB-T-1; ERBA; ERBA1; NR1A1; THRA; THRA1; THRA2; THRalpha; THRalpha1; THRalpha2; TRalpha; TRalpha1; TRalpha2
UniProt ID: (Human) P10827
Entrez Gene ID: (Human) 7067
transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
protein binding
zinc ion binding
TBP-class protein binding
protein domain specific binding
chromatin DNA binding
sequence-specific DNA binding
macromolecular complex binding
metal ion binding
thyroid hormone binding
general transcription initiation factor binding
negative regulation of transcription from RNA polymerase II promoter
cartilage condensation
ossification
thyroid hormone mediated signaling pathway
regulation of thyroid hormone mediated signaling pathway
positive regulation of thyroid hormone receptor signaling pathway
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
learning or memory
regulation of heart contraction
female courtship behavior
response to cold
hormone-mediated signaling pathway
organ morphogenesis
negative regulation of RNA polymerase II transcriptional preinitiation complex assembly
cell differentiation
erythrocyte differentiation
thyroid gland development
regulation of myeloid cell apoptotic process
mRNA transcription from RNA polymerase II promoter
negative regulation of transcription, DNA-templated
positive regulation of female receptivity
positive regulation of transcription from RNA polymerase II promoter
retinoic acid receptor signaling pathway
regulation of lipid catabolic process
Type I pneumocyte differentiation
positive regulation of cold-induced thermogenesis
negative regulation of DNA-templated transcription, initiation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
