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Invitrogen
THRAP4 Polyclonal Antibody
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产品信息
PA5-101073
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human MED24(Accession O75448), corresponding to amino acid residues V814-N864.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total MED24.
靶标信息
This gene encodes a component of the mediator complex, a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Activator-recruited cofactor 100 kDa component; ARC100; Cofactor required for Sp1 transcriptional activation subunit 4; cofactor required for Sp1 transcriptional activation, subunit 4, 100kDa; CRSP complex subunit 4; DRIP100; genetic suppressor element 2; hTRAP100; Mediator complex subunit 24; Mediator of RNA polymerase II transcription subunit 24; mediator of RNA polymerase II transcription, subunit 24 homolog; MGC8748; mTRAP100; peroxisome proliferation activation receptor binding protein 2; thyroid hormone receptor associated protein 4; thyroid hormone receptor-associated protein 100 kDa; Thyroid hormone receptor-associated protein 4; Thyroid hormone receptor-associated protein complex 100 kDa component; Trap100; Vitamin D3 receptor-interacting protein complex 100 kDa component; vitamin D3 receptor-interacting protein complex component DRIP100
基因别名: 911GSE; ARC100; AU040102; AW547152; CRSP100; CRSP4; D11Ertd307e; DRIP100; Gse2; KIAA0130; MED24; MED5; Pparb2; Pparbp2; R75526; THRAP4; TRAP100
UniProt ID: (Human) O75448, (Rat) Q4V8B3, (Mouse) Q99K74
Entrez Gene ID: (Human) 9862, (Rat) 619436, (Mouse) 23989
RNA polymerase II transcription cofactor activity
transcription cofactor activity
histone acetyltransferase activity
receptor activity
protein binding
ligand-dependent nuclear receptor transcription coactivator activity
vitamin D receptor binding
thyroid hormone receptor binding
ubiquitin protein ligase activity
transcription coactivator activity
general transcription factor
regulation of transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
protein ubiquitination
histone acetylation
stem cell population maintenance
intracellular steroid hormone receptor signaling pathway
androgen receptor signaling pathway
positive regulation of transcription, DNA-templated
protein heterooligomerization
transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
