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Abnova
THRAP5 Monoclonal Antibody (2B7)
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产品信息
H00010025-M02
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
2B7
抗原
THRAP5 (AAH17282, 1 a.a. approximately 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
See Label
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MCDLRRPAAG GMMDLAYVCE WEKWSKSTHC PSVPLACAWS CRNLIAFTMD LRSDDQDLTR MIHILDTEHP WDLHSIPSEH HEAITCLEWD QSGSRLLSAD ADGQIKCWSM
靶标信息
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DRIP92; MED16_i10; alternatively spliced; MED16_i11; alternatively spliced; MED16_i12; alternatively spliced; MED16_i13; alternatively spliced; MED16_i14; alternatively spliced; MED16_i15; alternatively spliced; MED16_i16; alternatively spliced; MED16_i17; alternatively spliced; MED16_i18; alternatively spliced; MED16_i19; alternatively spliced; MED16_i20; alternatively spliced; MED16_i21; alternatively spliced; MED16_i22; alternatively spliced; MED16_i23; alternatively spliced; MED16_i24; alternatively spliced; MED16_i25; alternatively spliced; MED16_i26; alternatively spliced; MED16_i27; alternatively spliced; MED16_i28; alternatively spliced; MED16_i29; alternatively spliced; MED16_i2; alternatively spliced; MED16_i30; alternatively spliced; MED16_i31; alternatively spliced; MED16_i32; alternatively spliced; MED16_i33; alternatively spliced; MED16_i34; alternatively spliced; MED16_i35; alternatively spliced; MED16_i3; alternatively spliced; MED16_i4; alternatively spliced; MED16_i5; alternatively spliced; MED16_i6; alternatively spliced; MED16_i7; alternatively spliced; MED16_i8; alternatively spliced; MED16_i9; alternatively spliced; Mediator complex subunit 16; Mediator of RNA polymerase II transcription subunit 16; thyroid hormone receptor associated protein 5; Thyroid hormone receptor-associated protein 5; thyroid hormone receptor-associated protein 95; Thyroid hormone receptor-associated protein complex 95 kDa component; thyroid hormone receptor-associated protein, 95-kD subunit; Trap95; Vitamin D3 receptor-interacting protein complex 92 kDa component
基因别名: 95kDa; A630083L04; DRIP92; GGNS; MED16; THRAP5; TRAP95
UniProt ID: (Human) Q9Y2X0, (Mouse) Q6PGF3
Entrez Gene ID: (Human) 10025, (Rat) 299607, (Mouse) 216154
transcription initiation from RNA polymerase II promoter
biological_process
intracellular steroid hormone receptor signaling pathway
androgen receptor signaling pathway
positive regulation of transcription, DNA-templated
positive regulation of receptor activity
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
regulation of transcription from RNA polymerase II promoter
positive regulation of transcription elongation from RNA polymerase II promoter
RNA polymerase II transcriptional preinitiation complex assembly
positive regulation of transcription initiation from RNA polymerase II promoter
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