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TIGAR Polyclonal Antibody
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TIGAR Antibody (600-401-FE4) in IHC (P)
Immunohistochemistry of TIGAR antibody. Tissue: Human brain tissue. Fixation: formalin fixed paraffin embedded. Antigen retrieval: not required. Primary antibody: TIGAR antibody at 2.5 µg/mL for 1 hr at RT. Secondary antibody: Peroxidase rabbit secondary antibody at 1:10,000 for 45 min at RT. Localization: TIGAR is cytoplasmic. Staining: TIGAR as precipitated red signal with hematoxylin purple nuclear count... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
600-401-FE4
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Anti-TIGAR antibody was prepared from whole rabbit serum produced by repeated immunizations with a 18 amino acid synthetic peptide from near the internal region of human TIGAR.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.2
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
This gene encodes a member of the kelch family of proteins, which are characterized by kelch repeat motifs and a POZ/BTB protein-binding domain. It is thought that kelch repeats are actin binding domains. However, the specific function of this protein has not been determined. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
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生物信息学
蛋白别名: fructose-2,6-bisphosphate 2-phosphatase; probable fructose-2,6-bisphosphatase TIGAR; TP53-induced glycolysis and apoptosis regulator; TP53-induced glycolysis regulatory phosphatase; transactivated by NS3TP2 protein; Trp53 induced glycolysis repulatory phosphatase; unnamed protein product
基因别名: 9630033F20Rik; C12orf5; FR2BP
UniProt ID: (Human) Q9NQ88, (Mouse) Q8BZA9
Entrez Gene ID: (Human) 57103, (Rat) 502894, (Mouse) 319801
response to ischemia
fructose 2,6-bisphosphate metabolic process
response to stress
cellular response to DNA damage stimulus
response to xenobiotic stimulus
response to gamma radiation
positive regulation of cardiac muscle cell apoptotic process
regulation of programmed cell death
negative regulation of programmed cell death
regulation of pentose-phosphate shunt
positive regulation of DNA repair
negative regulation of glycolytic process
positive regulation of phosphate metabolic process
intestinal epithelial cell development
cellular response to cobalt ion
cellular response to hypoxia
negative regulation of macromitophagy
regulation of response to DNA damage checkpoint signaling
positive regulation of hexokinase activity
negative regulation of glucose catabolic process to lactate via pyruvate
positive regulation of pentose-phosphate shunt
negative regulation of reactive oxygen species metabolic process
negative regulation of kinase activity
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
