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TIRP Polyclonal Antibody
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图: 1 / 3
TIRP Antibody (200-401-FF4) in ICC/IF
Immunocytochemistry of Rabbit anti-TIRP antibody. Cell Type: Raji cells. Fixation: formalin fixed paraffin embedded. Antigen retrieval: not required. Primary antibody: TIRP antibody at 10 µg/mL for 1 hr at RT. Secondary antibody: Peroxidase rabbit secondary antibody at 1:10,000 for 45 min at RT. Localization: TIRP is located in the cellular membrane. Staining: TIRP is stained brown with hematoxylin purple nuclear counterstain.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
200-401-FF4
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Anti-TIRP antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to 16 amino acids at the C-terminus of human TIRP.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Ion-exchange chromatography
保存液
PBS, pH 7.2
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
TRAM, or TRIF-related adaptor molecule (TICAM2), plays an essential role in the MyD88-independent signaling of TLR4. The functional absence of TRAM in vascular endothelial cells restricts TLR4 signaling to MyD88-dependent pathway. Overexpression of TRAM cDNA in endothelial cells reconstituted LPS-induced Trif-dependent NF-kB activation and cxcl10 promoter activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cytoplasmic adaptor; NF-kappa-B-activating protein 502; putative NF-kappa-B-activating protein 502; TAG; TLR adapter molecule; toll like receptor adaptor molecule 2; toll-like receptor adaptor protein 3; toll/interleukin-1 receptor (TIR) domain-containing adapter protein; TRIF-related adaptor molecule
基因别名: MyD88-4; TICAM-2; TIRAP3; TIRP; TRAM
UniProt ID: (Human) Q86XR7
Entrez Gene ID: (Human) 353376
phagocytosis
signal transduction
lipopolysaccharide-mediated signaling pathway
positive regulation of type I interferon production
toll-like receptor 4 signaling pathway
negative regulation of toll-like receptor 4 signaling pathway
positive regulation of toll-like receptor 4 signaling pathway
TRIF-dependent toll-like receptor signaling pathway
TRIF-dependent toll-like receptor 4 signaling pathway
TRAM-dependent toll-like receptor 4 signaling pathway
positive regulation of I-kappaB kinase/NF-kappaB signaling
innate immune response
response to other organism
cellular response to lipopolysaccharide
negative regulation of chemokine (C-C motif) ligand 5 production
positive regulation of chemokine (C-C motif) ligand 5 production
positive regulation of interleukin-18-mediated signaling pathway
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
