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Positive test controls include: HeLa, 293T, Jurkat, Mouse liver, Mouse spleen, Mouse stomach, Rat liver, Rat spleen, Rat stomach. The target is usually found in the following locations: Cytoplasm.
Immunogen sequence: SKTRGQIQVI LGPMFSGKST ELMRRVRRFQ IAQYKCLVIK YAKDTRYSSS FCTHDRNTME ALPACLLRDV AQEALGVAVI GIDEGQFFPD IVEFCEAMAN AGKTVIVAAL DGTFQRKPFG AILNLVPLAE SVVKLTAVCM ECFREAAYTK RLGTEKEVEV IGGADKYHSV CRLCYFKKAS
Thymidine Kinase (TK1) is a highly conserved phosphotransferase that is present in most living cells. Thymidine Kinase catalyzes the phosphorylation reaction: deoxythymidine + ATP = deoxythymidine 5'-phosphate + ADP; it is thus involved in the reaction chain to introduce deoxythymidine into the DNA. Thymidine kinase is required for the action of many antiviral drugs, such as azidothymidine (AZT), and is also used to select hybridoma cell lines in the production of monoclonal antibodies. Thymidine Kinase has many clinical applications as it is only present in anticipation of cell division.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: EC 2.7.1.21; KITH; thymidine kinase 1 soluble isoform; thymidine kinase 1, soluble; Thymidine kinase, cytosolic; thymidine kinase-1
基因别名: D530002A18Rik; Tk; Tk-1; TK1; Tk1a; Tk1b; TK2
UniProt ID: (Human) P04183, (Rat) P27158, (Mouse) P04184
Entrez Gene ID: (Human) 7083, (Rat) 24834, (Mouse) 21877