Invitrogen

TK1 Polyclonal Antibody

TK1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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TK1 Antibody (PA5-29686) in IHC (P)

TK1 Polyclonal Antibody detects Thymidine Kinase 1 protein at cytoplasm by immunohistochemical analysis. Sample: Paraffin-embedded rat ovary. Thymidine Kinase 1 stained by TK1 Polyclonal Antibody (Product # PA5-29686) diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.

TK1 Antibody in Immunohistochemistry (IHC)

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产品信息

PA5-29686

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:3,000

免疫组化 (IHC)

查看1篇已发表文章 1篇已发表文章

免疫组化（石蜡） (IHC (P))

1:100-1:1,000

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fragment corresponding to a region within amino acids 1 and 223 of Human Thymidine Kinase 1

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1.01 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7, with 20% glycerol

内含物

0.025% ProClin 300

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2547160

产品详细信息

Recommended positive controls: A431, A431 cytoplasm extract.

Predicted reactivity: Mouse (91%), Rat (91%), Zebrafish (81%), Chicken (83%), Bovine (92%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

靶标信息

Thymidine Kinase (TK1) is a highly conserved phosphotransferase that is present in most living cells. Thymidine Kinase catalyzes the phosphorylation reaction: deoxythymidine + ATP = deoxythymidine 5'-phosphate + ADP; it is thus involved in the reaction chain to introduce deoxythymidine into the DNA. Thymidine kinase is required for the action of many antiviral drugs, such as azidothymidine (AZT), and is also used to select hybridoma cell lines in the production of monoclonal antibodies. Thymidine Kinase has many clinical applications as it is only present in anticipation of cell division.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Chemokine Analysis in Patients with Metastatic Uveal Melanoma Suggests a Role for CCL21 Signaling in Combined Epigenetic Therapy and Checkpoint Immunotherapy.

Cancer research communications

Sah VR,Jespersen H,Karlsson J,Nilsson LM,Bergqvist M,Johansson I,Carneiro A,Helgadottir H,Levin M,Ullenhag G,Ståhlberg A,Olofsson Bagge R,Nilsson JA,Ny L

Published figure using TK1 polyclonal antibody (Product # PA5-29686) in Immunohistochemistry

Mon May 01 00:00:00 EDT 2023

Chemokine Analysis in Patients with Metastatic Uveal Melanoma Suggests a Role for CCL21 Signaling in Combined Epigenetic Therapy and Checkpoint Immunotherapy.

Cancer research communications

Sah VR,Jespersen H,Karlsson J,Nilsson LM,Bergqvist M,Johansson I,Carneiro A,Helgadottir H,Levin M,Ullenhag G,Ståhlberg A,Olofsson Bagge R,Nilsson JA,Ny L