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Invitrogen
TK1 Polyclonal Antibody
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图: 1 / 2
TK1 Antibody (PA5-99500) in ICC/IF
Immunofluorescent analysis of TK1 in MCF-7 cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% saponin, blocked with 10% serum (45 min, 37°C) incubated with TK1 polyclonal antibody (Product # PA5-99500) using a dilution of 1:400 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 at a dilution of 1:600.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-99500
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human TK1(Accession P04183), corresponding to amino acid residues M1-M37.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total Thymidine Kinase 1/TK1.
靶标信息
Thymidine Kinase (TK1) is a highly conserved phosphotransferase that is present in most living cells. Thymidine Kinase catalyzes the phosphorylation reaction: deoxythymidine + ATP = deoxythymidine 5'-phosphate + ADP; it is thus involved in the reaction chain to introduce deoxythymidine into the DNA. Thymidine kinase is required for the action of many antiviral drugs, such as azidothymidine (AZT), and is also used to select hybridoma cell lines in the production of monoclonal antibodies. Thymidine Kinase has many clinical applications as it is only present in anticipation of cell division.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EC 2.7.1.21; KITH; Thymidine kinase, cytosolic
基因别名: D530002A18Rik; Tk; Tk-1; TK1; Tk1a; Tk1b
UniProt ID: (Rat) P27158, (Mouse) P04184
Entrez Gene ID: (Rat) 24834, (Mouse) 21877
liver development
deoxyribonucleoside monophosphate biosynthetic process
nucleotide biosynthetic process
response to toxic substance
skeletal muscle cell proliferation
phosphorylation
response to nutrient levels
thymidine metabolic process
response to copper ion
digestive tract development
protein homotetramerization
response to cortisol
fetal process involved in parturition
DNA biosynthetic process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
